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Arizona Cardinals’ Quarter-Century Team: The Most Impactful Players Since 2000

Arizona Cardinals’ Quarter-Century Team: The Most Impactful Players Since 2000

April 8, 2025 11:24am

While much of the last quarter-century has been anything but memorable for fans of the Arizona Cardinals, that’s not to say that there haven’t been players that were worth remembering in the Valley. With that in mind, BetArizona.com broke down the best players to don Sedona red since 2000 in all three facets of the game, broken down by position using the approximate value totals that Pro-Football-Reference.com compiles each year.

Cardinals’ Quarter-Century Offense

Position	Player	Years With Team	Approximate Value During Years
QB	Kyler Murray	2019-Present	77
RB	David Johnson	2015-2019	36
WR	Larry Fitzgerald	2004-2020	138
WR	Anquan Boldin	2003-2009	63
TE	Trey McBride	2022-Present	21
OT	DJ Humphries	2016-2023	50
G	Reggie Wells	2003-2009	44
C	Lyle Sendlein	2007-2015	57
G	Leonard Davis	2001-2006	39
OT	Levi Brown	2007-2013	37

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Offensively, the greatest member of the Cardinals franchise over the last 25 years (and the most valuable player in Arizona history, AV wise, period) has been wideout Larry Fitzgerald, whose 138 AV total in 263 games with the club from 2004 to 2020 nearly double the next closest team member during that time period.

That player is former No. 1 pick Kyler Murray, who has 77 AV in 82 games with the Cardinals since being drafted atop the 2019 NFL Draft, with the Heisman Trophy winner out of Oklahoma ranking ahead of wideout Anquan Boldin, who finished with the third most AV points of any Arizona offensive player between 2000 and 2024, at 63.

Also of interest: 65 Kyler Murray Fantasy Football Team Names to Use in 2025.

Throw in other franchise-caliber Cardinals players like center Lyle Sendlein (57 AV in 136 games between 2007 and 2015), offensive tackle D.J. Humphries (50 AV in 98 games from 2016 to 2023) and guard Reggie Wells (44 AV in 104 games between 2003 and 2009) and you have the upper end of the Arizona AV offensive list covered.

Of the top AV earners by offensive position, only Murray and tight end Trey McBride (21 AV in 49 games since 2022) are still playing for the Cardinals, with the most recent ex-Arizona player being Humphries, who left the Valley back in 2023, while Fitzgerald’s playing days ended in 2020.

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Cardinals’ Quarter-Century Defense

Position	Player	Years With Team	Approximate Value During Years
DE	Calais Campbell	2008-2016	82
DT	Darnell Dockett	2004-2013	86
DE	Chandler Jones	2016-2021	56
LB	Karlos Dansby	2004-2017	68
LB	Daryl Washington	2010-2013	36
LB	Ronald McKinnon	2000-2005	35
CB	Patrick Peterson	2011-2020	114
S	Adrian Wilson	2001-2012	85
S	Budda Baker	2017-Present	67
CB	Dominique Rodgers-Cromartie	2008-2010	21

On the defensive side of the ball, few players have achieved more for the Cardinals than cornerback Patrick Peterson, who had 114 AV in 154 games with the franchise between 2011 and 2020, ranking fifth all time on the franchise’s AV leaderboard.

Overall, Peterson ranked ahead of other Arizona defensive stars like Darnell Dockett, who had 86 AV at the defensive tackle spot for Arizona between 2004 and 2013, while safety Adrian Wilson had 85 AV at safety between 2001 and 2012.

Other top tier defensive players for the club, AV wise, were defensive end Calais Campbell (82 AV in 138 games from 2008 to 2016), linebacker Karlos Dansby (68 AV in 122 games between 2004 and 2017), Budda Baker (67 AV from 2017 to present) and defensive end Chandler Jones (56 AV from 2016 to 2021).

Of the top AV earners on the defensive side of the ball since 2000, Baker is the only player still employed by the Cardinals, with the most recent expat being Jones, who left the Valley back in 2021.

Cardinals’ Quarter-Century Special Teams

Position	Player	Years With Team	Approximate Value During Years
K	Neil Rackers	2003-2009	24
P	Andy Lee	2017-2022	17

Finally, on the specialist side of the game, the two players that earned the most AV in the Valley were kicker Neil Rackers, who had 24 AV in 100 games for the club from 2003 to 2009, while punter Andy Lee racked up 17 AV between 2017 and 2022.

Of the two, Rackers played the most games for the Cardinals, suiting up 100 times for Arizona. Lee played in 96 games with Arizona after starting his NFL career in the Bay Area with Arizona’s NFC West rivals, the San Francisco 49ers, where he played for 11 seasons with 33 AV in 176 games with the club.

Stick with BetArizona for more Cardinals content and news around Arizona sports betting.

USA Today photo by Michael Chow.

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Author

Christopher Boan

Christopher Boan is the lead writer at BetArizona.com after covering sports and sports betting in Arizona for more than seven years, including stops at ArizonaSports.com, the Tucson Weekly and the Green Valley News.

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